BRCA Mutation Carriers' Platform a Multicenter Study
Recruiting
Observational Study
BRCA1 Mutation
BRCA2 Mutation
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Female
- Study type
- Observational
- Participants needed
- 10,000 (estimated)
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Other
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About This Trial
Subjects who carry mutations in breast cancer susceptibility genes 1 and 2 (BRCA1 and BRCA2 genes) are at higher risk of developing cancers. Despite the cumulative amount of evidence published in the literature in the last two decades, the management of BRCA mutation carriers is still not completely defined.
Since the prevalence of the mutation is estimated to be 1:400 - 1:500 individuals, the to…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* All women who are 18 years of age or older;
* All women who known to be carriers of a pathogenetic mutation class 4 and 5 of the International Agency of Research on Cancer classification) of the BRCA1 or BRCA2 genes.
Exclusion Criteria:
* Age \< 18 years old;
* No pathogenet…
Contacts