Comperative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation in Subacute Stroke Patients
Recruiting
N/AInterventional Study
StrokeStroke, Acute
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
45 – 70
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
54 (estimated)
Sponsor
Lahore University of Biological and Applied Sciences · Other
Who this trial is looking for
This trial is looking for people who have had their first ischemic stroke and are between 3 to 6 months post-stroke. Participants will receive a type of nerve stimulation along with specific training to help improve their motor skills and quality of life.
Are You a Good Fit for This Trial?
You may be able to join if
I have had my first ischemic stroke.
I am 3 to 6 months post-stroke.
I have a Fugl-Meyer Assessment score between 20 and 50.
You may not be able to join if
I have had previous surgery on my vagus nerve.
I have experienced cardiac arrest or have heart rhythm issues.
I have uncontrolled high blood pressure.
I have apraxia.
I have other neurological or musculoskeletal diseases.
I have implanted electronic devices.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
This study aims to determine whether transcutaneous vagus nerve stimulation (tVNS) via auricular or cervical branches enhances recovery when combined with task-specific training in subacute stroke patients. We anticipate finding that both stimulation methods may improve upper limb motor function compared to conventional therapy. The research is expected to reveal specific cognitive domains (attent…
This study aims to determine whether transcutaneous vagus nerve stimulation (tVNS) via auricular or cervical branches enhances recovery when combined with task-specific training in subacute stroke patients. We anticipate finding that both stimulation methods may improve upper limb motor function compared to conventional therapy. The research is expected to reveal specific cognitive domains (attention, memory, executive function) that benefit most from each stimulation approach, while also demonstrating meaningful improvements in patients' quality of life measures. These findings may make a significant practical contribution by providing clinicians with evidence-based guidance on suitable tVNS approach for improving functional independence and quality of life for stroke survivors.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* First ever ischemic stroke
* Subacute phase of stroke 3-6 months post onset
* Fugl-Meyer Assessment-Upper Extremity (FMA-UE) scores ranged from 20 - 50
Exclusion Criteria:
* Previous injury or surgical intervention of vagus nerve
* Patients with cardiac arrest and arrythmias…
Inclusion Criteria:
* First ever ischemic stroke
* Subacute phase of stroke 3-6 months post onset
* Fugl-Meyer Assessment-Upper Extremity (FMA-UE) scores ranged from 20 - 50
Exclusion Criteria:
* Previous injury or surgical intervention of vagus nerve
* Patients with cardiac arrest and arrythmias
* Uncontrolled hypertension
* Apraxia
* Other neurologic or musculoskeletal diseases
* Presence of implanted electronic devices
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