Effect of VExUS Ultrasound Protocol (Venous Excess Ultrasound) on Perioperative Fluid Management, on the Incidence of Postoperative Pulmonary Complications and Postoperative Acute Kidney Injury in Patients Undergoing Thoracic Surgery
Recruiting
N/AInterventional Study
Thoracic Surgery With One-lung VentilationVExUSFluid ManagementAcute Kidney InjuryPostoperative Pulmonary Complications (PPCs)
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
230 (estimated)
Sponsor
University of Crete · Other
Who this trial is looking for
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This study aims to investigate the effect of a VExUS ultrasound guided protocol of perioperative fluid management within a goal-directed therapy framework, on postoperative respiratory complications, and the occurrence of acute kidney injury (AKI) in patients undergoing thoracic surgery.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adults \>18 years undergoing video assisted thoracic surgery/ lobectomy requiring one-lung ventilation.
Exclusion Criteria:
* Refusal to participate.
* Pneumonectomy.
* Young athletes (risk of physiologically large IVC \>2 cm).
* Moderate-severe tricuspid regurgitation, mode…
Inclusion Criteria:
* Adults \>18 years undergoing video assisted thoracic surgery/ lobectomy requiring one-lung ventilation.
Exclusion Criteria:
* Refusal to participate.
* Pneumonectomy.
* Young athletes (risk of physiologically large IVC \>2 cm).
* Moderate-severe tricuspid regurgitation, moderate to severe pulmonary hypertension
* Heart failure with reduced ejection fraction, EF\<35%
* Portal hypertension, portal vein thrombosis, or liver cirrhosis.
* Stage 4 or end-stage chronic kidney disease (eGFR \<30 mL/min/1.73 m² or dialysis).
* Transfusion with more than 2 packed red blood cells unit perioperatively (intraoperatively, in the PACU, in the ward)
Contacts
Alexandros Bogas Manouselis, Resident of Anaesthesiology
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