Minto and Eleveld Remifentanil Target Controlled Infusion (TCI) Models: a Clinical Comparison

Recruiting Observational Study
Propofol Anesthesia Brain Monitoring Remifentanil
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 80
Sex
Female
Study type
Observational
Participants needed
100 (estimated)
Sponsor
University of Padova · Other
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About This Trial
Remifentanil is commonly used as an opioid during general anesthesia. In recent years, several pharmacokinetic/pharmacodynamic (PK/PD) models for target-controlled infusion (TCI) have been developed, with the Eleveld model being one of the most recent and designed for broad applicability. The aim of this study is to compare the Eleveld TCI model with the routinely used Minto model, in order to ev…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Undergo general anaesthesia with Targeted Controlled Infusion of Propofol (Eleveld model) and Remifentanil (Minto or Eleveld model) Exclusion Criteria: * Neurological disease * Psychiatric disease
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