A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biologic Effect of VG2062 in Patients With Solid Tumors

Recruiting Phase 1 Interventional Study
Advanced Malignant Solid Tumor
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 75
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
30 (estimated)
Sponsor
Shanghai Virogin Biotech Co., Ltd. · Industry
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About This Trial

VG2062 is a Recombinant Human IL12/15 Dual-Regulated Oncolytic HSV-1 Injection. This Phase I study will be conducted in herpes simplex virus (HSV) -seropositive subjects with advanced malignant solid tumors that are refractory to conventional therapies. This is an open label study to determine the safety and tolerability of VG2062, and recommended dose of VG2062 for Phase II trials.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Signed written informed consent form. 2. Age 18 to 75 years (inclusive), male or female. 3. Subject with advanced malignant solid tumors who have failed standard treatment and for whom there is no effective treatment at this stage. 4. Eligible patients of childbearing potenti…
Contacts

Shu hang Wang

13581809307

wangshuhang@cicams.ac.cn

CONTACT