Evaluation of the Association Between the Effects of Generalized Stage 3 and 4 Periodontitis on Arterial Stiffness and Cardiovascular Risk: the PAROCAR Study

Recruiting N/A Interventional Study
Periodontis Atherosclerosis Cardiovascular Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
40 – 69
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
206 (estimated)
Sponsor
Nantes University Hospital · Other
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About This Trial
Periodontal diseases are chronic inflammatory conditions affecting nearly half of the adult population and are associated with systemic inflammatory responses. Recent evidence suggests a possible link between severe periodontitis and cardiovascular diseases through shared inflammatory pathways. The PAROCAR study aims to evaluate the association between generalized periodontitis (stages 3 and 4, 2…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age 40-69 years * Minimum of 12 teeth (3 per quadrant) * Written informed consent Exposed group: generalized periodontitis stage 3 or 4 (Chicago 2017 Classification) Non-exposed group: healthy periodontium Exclusion Criteria: * Patients diagnosed with diabetes, * Patients di…
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