PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)

Recruiting Observational Study
Pre-eclampsia Oocyte Donation Pre-Eclampsia; Complicating Pregnancy Pre-Eclampsia; Mild Pre-Eclampsia, Severe Pre-eclampsia or Eclampsia With Pre-existing Hypertension ART Neonatal Morbidity Neonatal Mortality Placental Abruption Gestational Diabetes Preterm Labor Post-partum Hemorrhage (PPH) Intrauterine Growth Restriction (IUGR) Hypertensive Disorders of Pregnancy
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Female
Study type
Observational
Participants needed
462 (estimated)
Sponsor
Copenhagen University Hospital, Hvidovre · Other
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About This Trial
The aim of this prospective observational cohort study is to investigate the pathophysiological mechanisms behind and risk of pre-eclampsia in women pregnant after fertility treatment with oocyte donation. The participants are included in of of two cohorts. One includes women pregnant after oocyte donation whereas the other includes women pregnant after IVF treatment with autologous oocytes. Part…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age \> 18 years * BMI \< 35 kg/m2 * Normal wet smear within the past three years * Both nulli- and multiparous * Singletons and multiple gestations Exclusion Criteria: * Age \< 18 years * BMI \> 35 kg/m2 * HIV/ hepatitis * Essential hypertension * Chronic kidney disease * Un…
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