SUCCESS Score Validation in Fuchs Dystrophy
Recruiting
Observational Study
Fuchs Endothelial Corneal Dystrophy
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 40 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 250 (estimated)
- Sponsor
- Instituto Ramón y Cajal de Investigación Sanitaria · Other
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About This Trial
This prospective multicenter diagnostic study aims to externally validate and extend the SUCCESS Score for predicting the need for endothelial keratoplasty after cataract surgery in patients with Fuchs endothelial corneal dystrophy (FECD). The model's performance and clinical utility are assessed using discrimination, calibration, and reclassification metrics.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adults aged ≥40 years.
* Clinical diagnosis of Fuchs endothelial corneal dystrophy (FECD) grade ≥2 on the modified Krachmer scale.
* Presence of visually significant cataract requiring phacoemulsification surgery.
* Ability to provide informed consent and comply with study pro…
Contacts