Two Post-Operative Pain Protocols at Discharge for Orthopaedic Patients

Recruiting N/A Interventional Study
Orthopaedic Related Pain (Musculoskeletal Pain) Opioid Pain Pilot Study
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
100 (estimated)
Sponsor
Massachusetts General Hospital · Other
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About This Trial

This is a single-center, pilot randomized controlled trial designed to evaluate the feasibility of a definitive trial comparing opioid-free discharge prescriptions to usual care (which includes opioids) in patients undergoing major orthopaedic surgery. The main objective is to inform the design and feasibility of the definitive RCT.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Patients 18 years of age or older 2. Underwent a major operative orthopaedic procedure Exclusion Criteria: 1. Contraindication for NSAIDs. 2. Preoperative chronic opioid use (preoperative use of \>14 days and average of \>30 Morphine Milligram Equivalents per day). 3. Activ…
Contacts

Arun Aneja, MD, PhD

617-726-6546

aaneja@mgh.harvard.edu

CONTACT

Sheila Sprague, PhD

sprags@mcmaster.ca

CONTACT