Analysis of Methylomic Features and Prognostic Risk Prediction in Patients With Hepatitis B-related Acute-on-chronic Liver Failure
Recruiting
Observational Study
HBV Related Acute-on-chronic Liver Failure
HBV-related Liver Cirrhosis
HBV (Hepatitis B Virus)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 100 (estimated)
- Sponsor
- Qilu Hospital of Shandong University · Other
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About This Trial
This study aims to investigate the methylomic features of patients with hepatitis B-related acute-on-chronic liver failure and establish and validate a prognostic risk prediction classification model. The findings are of significant importance for guiding clinical practice and improving patient prognosis. Additionally, a methylomics-based classifier model for liver failure will be developed for di…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Chronic hepatitis B was persistent hepatitis B surface antigen (HBsAg) seropositivity for more than six months.
Hepatitis B-related liver cirrhosis was diagnosed based on histological examination, typical features on ultrasound or radiological imaging, endoscopic findings of …
Contacts