AZD1163 for Rheumatoid Arthritis

A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

Recruiting Phase 2 Interventional Study
Rheumatoid Arthritis
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
320 (estimated)
Sponsor
AstraZeneca · Industry
Who this trial is looking for

This trial is looking for people with moderately-to-severely active rheumatoid arthritis. Participants will be evaluated for how well the medication AZD1163 works and its safety.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been diagnosed with rheumatoid arthritis for at least 12 weeks.
  • I have at least 6 swollen joints and 6 tender joints.
  • My CRP levels are above normal.
  • I have a positive ACPA test.
  • I have not responded well to at least one csDMARD treatment or 1-2 TNFi.
  • I have been on a stable dose of csDMARD or SC TNFi for at least 4 weeks.

You may not be able to join if

  • I have a history of another autoimmune condition that could confuse my RA diagnosis.
  • I plan to receive any biologic DMARDs (other than TNFi).
  • I have received any targeted synthetic DMARDs.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial

Phase II study in participants with moderately-to-severely active rheumatoid Arthritis (RA) to evaluate efficacy and safety of AZD1163.

Trial Locations
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Eligibility Criteria
* Inclusion * Diagnosed with adult-onset RA as defined by the 2010 ACR/EULAR classification criteria for at least 12 weeks prior to screening. * Moderately-to-severely active RA as defined by: a. \>= 6 swollen joints on 66SJC and \>= 6 tender joints on 68TJC; b. CRP \> upper limit of normal. …
Contacts

AstraZeneca Clinical Study Information Center

1-877-240-9479

information.center@astrazeneca.com

CONTACT