ABBV901 for Advanced Ovarian Cancer

A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous (IV) ABBV901 Moves Through the Body Alone or in Combination With Other Anticancer Drugs in Adult Participants With Ovarian Cancer

Recruiting Phase 1 Interventional Study
Ovarian Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
285 (estimated)
Sponsor
AbbVie · Industry
Who this trial is looking for

This trial is looking for adults with advanced ovarian cancer who have already received other treatments. Participants will take the drug ABBV901 alone or with another treatment called bevacizumab, and they will have regular visits for medical assessments and tests.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been diagnosed with advanced high grade serous ovarian cancer.
  • I am considered platinum resistant or platinum ineligible.
  • I have received prior standard cancer treatments.
  • I have had at most 2 prior treatments since my cancer became platinum resistant.

You may not be able to join if

  • I have a type of ovarian cancer other than high grade serous.
  • I have received prior treatment with specific antibody-drug conjugates.
  • I have a history of serious lung issues.
  • I have active lung disease that needs treatment.
  • I have used certain strong medications that affect liver enzymes recently.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
Ovarian cancer (OC) is a lethal disease. The purpose of this study is to assess the safety, pharmacokinetics and efficacy of ABBV901, alone or in combination with other anticancer drugs, in participants with ovarian cancer. ABBV901 is an investigational drug for the treatment of ovarian cancer. This study has 6 parts where participants will receive ABBV-901, alone or in combination with other ant…
Trial Locations
Loading…

Loading trial locations…

Eligibility Criteria
Inclusion Criteria: * Diagnosis of an advanced or unresectable malignant high grade serous epithelial ovarian, fallopian tube, and primary peritoneal cancers (EOC), fallopian tube or primary peritoneal cancer by histology (World Health Organization \[WHO\] criteria). * Participants enrolled in back…
Contacts

ABBVIE CALL CENTER

844-663-3742

abbvieclinicaltrials@abbvie.com

CONTACT