Epigenetic Profiling and Liquid Biopsy: Perspectives for Personalized Medicine in Meningioma Patients - MIND
Recruiting
Observational Study
Meningioma
Meningioma of Brain
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 210 (estimated)
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Other
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About This Trial
Meningiomas are the most common primary intracranial tumors. Current treatment relies on surgical resection and radiotherapy, but molecular predictors for recurrence are lacking. This study aims to investigate epigenetic features, specifically histone post-translational modifications (PTMs) and DNA methylation, to stratify patients. The study involves a retrospective cohort to define an epigenetic…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Inclusion Criteria (Retrospective \& Prospective):
* Patient aged 18 years or older.
* First diagnosis of uni-focal meningioma of the convexity.
* Macroscopical total resection (Simpson 1-3).
(Retrospective only):
* Surgery performed between 2007 and 2016;
* availability of F…
Contacts
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