Prospective Observational Cohort Study of Cardiac Structure and Function in Children and Adults With Osteogenesis Imperfecta
Recruiting
Observational Study
Osteogenesis Imperfecta (OI)
Osteogenesis Imperfecta
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 5 – 80
- Sex
- Any
- Study type
- Observational
- Participants needed
- 40 (estimated)
- Sponsor
- Istituto Ortopedico Rizzoli · Other
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About This Trial
This prospective observational investigation will examine the incidence and progression of cardiologic findings in individuals with OI across different age groups. Cardiopulmonary complications are recognized as major contributors to morbidity and mortality in adults with OI, although life expectancy has significantly improved in recent years due to medical advancements.
By systematically evaluat…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Diagnosis of OI according to the modified Sillence classification (Mortier et al., 2019)
* All subjects with OI who attend genetic consultations at the clinic affiliated with the Rare Skeletal Diseases Unit of the IRCCS Rizzoli Orthopaedic Institute (IOR)
* Willingness to unde…
Contacts
No contact information available.