Post-transplantation Maintenance Therapy With Cidabenamide in Patients With Intermediate/High-risk AML

Recruiting Phase 2 Interventional Study
Allogeneic Hematopoietic Cell Transplantation (HCT) AML (Acute Myeloid Leukemia)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 75
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
134 (estimated)
Sponsor
Institute of Hematology & Blood Diseases Hospital, China · Other
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About This Trial
This study is a Phase II clinical trial designed to evaluate the efficacy and safety of Chidamide as maintenance therapy in high-risk acute myeloid leukemia (AML) patients following stem cell transplantation. Trial Design: The trial is a single-arm, open-label study. The experimental group plans to enroll 67 patients, while the control group (observation only) also plans to enroll approximately 6…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. AML patients meeting the following conditions (diagnosed per WHO 2022 AML criteria) who achieved first complete remission (CR) with intermediate-/high-risk cytogenetic abnormalities at the time of allogeneic transplantation. 2. Patients must achieve complete remission (CR) po…
Contacts

Jiang Erlie, doctor

+86-15122538106

jiangerlie@ihcams.ac.cn

CONTACT

Liang Chen

+86-13612043271

liangchen@ihcams.ac.cn

CONTACT