Intravesical Lactobacillus Crispatus: Clinical Safety and Microbiome Evaluation
Recruiting
Early Phase 1
Interventional Study
Spinal Cord Injuries (SCI)
Neurogenic Bladder
Urinary Tract Infection (Diagnosis)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 40 (estimated)
- Sponsor
- Medstar Health Research Institute · Other
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
The goal of this clinical trial is to determine whether Lactobacillus crispatus strains isolated from the lower urinary tracts of adult women can be used as an antibiotic-sparing treatment for urinary symptoms and urinary tract infection (UTI) among adults with neurogenic lower urinary tract dysfunction (NLUTD). The main question\[s\] it aims to answer are:
1. To identify soluble bactericidal com…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
* Age ≥ 18 years
* SCI with at least 6-month duration
* NLUTD
* Utilizing intermittent catheterization for bladder management
* Community dwelling
Exclusion Criteria:
* Use of prophylactic antibiotics
* Instillation of intravesical antimicrobials to prevent UTI
* Psychological…
Contacts