External Validation of the CLOVER Score for Detecting Occult Cancer in Venous Thromboembolism Patients
Recruiting
Observational Study
Venous Thromboembolism (VTE)
Occult Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 500 (estimated)
- Sponsor
- Infanta Leonor University Hospital · Other
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About This Trial
This study aims to externally validate the CLOVER score, a machine learning-based predictive model designed to identify patients with venous thromboembolism (VTE) who are at increased risk of having an occult cancer. The study includes a retrospective cohort of patients with acute symptomatic VTE diagnosed between 2000 and 2022, and a prospective cohort of consecutively recruited patients from Dec…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age ≥18 years.
* Objectively confirmed acute symptomatic venous thromboembolism (deep vein thrombosis and/or pulmonary embolism).
* Ability to provide written or electronic informed consent.
Exclusion Criteria:
* Suspicion of cancer during the initial diagnostic evaluation f…
Contacts