Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder
Recruiting
Phase 4
Interventional Study
Cocaine Use Disorder
Crack Abuse or Dependence
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 36 (estimated)
- Sponsor
- University of Sao Paulo General Hospital · Other
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About This Trial
This is a single-center, randomized intervention study in a volunteer population of patients with cocaine/crack use disorder to evaluate the pharmacological treatment of cocaine/crack craving, comparing the drug clonidine with the active placebo clonazepam.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients hospitalized in the adult Alcohol and Drugs ward of the Perdizes Institute (IPer) at the Hospital das Clínicas, University of São Paulo Medical School
* DSM-5 criteria for cocaine and/or crack use disorder
* Voluntarily seeking treatment
* Must be able to swallow pill…
Contacts