Viability Assessment Using FMN Measured in Perfusate and Bile During Normothermic Machine Perfusion

Recruiting Observational Study
Liver Transplant Disorder
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
850 (estimated)
Sponsor
The Cleveland Clinic · Other
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About This Trial
Discarded perfusate samples will be collected from donors after circulatory death (DCD) or donors after brain death (DBD) organs during the machine perfusion period prior to transplantation by the study team. FMN will be measured as is standard of care for all machine perfusion liver transplant cases at Cleveland Clinic. Participating centers will be provided with sample collection and shipping i…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age \>18 years * Any graft type (DBD or DCD) * Any underlying recipient disease (i.e., end stage, liver tumour) * Any other donor risk factors and static cold storage time prior to NMP accepted by the participating center for transplantation in context of OrganOx metra use * P…
Contacts

Mary Bilancini, MS

216-444-8983

bilancm@ccf.org

CONTACT

Erlind Allkushi, BS

216-444-0223

allkuse2@ccf.org

CONTACT