A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function
Recruiting
Phase 1
Interventional Study
Renal Impairment
Healthy
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 28 (estimated)
- Sponsor
- Pfizer · Industry
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About This Trial
The purpose of this study is to learn how the study medicine PF-07328948 is processed by the body and how safe and tolerable it is in adults with different levels of kidney function.
The study will include participants who:
* Are aged 18 to 80 years.
* Either have normal kidney function or long-term reduced kidney function (moderate or severe).
* Have a BMI (body mass index) of 17.5 to 40 kilogr…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Male or female of nonchildbearing potential, between the ages of 18 and 80 years, at the screening visit.
* BMI of 17.5 to 40.0 kg/m2 (inclusive), and a total body weight ≥45 kg (99 lbs).
* Stable renal function, defined as ≤25% difference between 2 measurements of eGFR.
* Gro…
Contacts