Personalized Atrial Fibrillation Ablation Guided by Non-Invasive Global Mapping
Recruiting
N/A
Interventional Study
Atrial Fibrillation (AF)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 45 (estimated)
- Sponsor
- German Heart Institute · Other
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About This Trial
This pilot study investigates if non-invasive global mapping can guide catheter ablation of atrial fibrillation (AF) by defining personalized targets based on the temporal Stability of local Atrial High-Rate Activity (SAHRA). The study also assesses efficacy and safety of this approach and evaluates potential signals of harm. The main questions it aims to answer are:
* Does ablation of targets de…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Ablation-naïve patients with:
1. Persistent AF planned for catheter ablation plus
2. Left atrial enlargement (LA diameter ≥45 mm or LA volume index ≥35ml/m2 or LA area ≥20 cm2)
Exclusion Criteria:
* Previous cardiac ablation
* Age \<18 years
* Pregnancy or lactation
* Previou…
Contacts