Effects of Physical Activity and Fitness, Cardiovascular- and Psychosocial Health on Medically Assisted Reproduction
Recruiting
Observational Study
Infertility, Female
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 43
Sex
Female
Study type
Observational
Participants needed
115 (estimated)
Sponsor
University Hospital, Basel, Switzerland · Other
Who this trial is looking for
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This prospective observational study aims to investigate the association between physical activity and clinical pregnancy rates in women undergoing medically assisted reproduction. Additionally, it evaluates how cardiorespiratory fitness, cardiovascular health, psychosocial factors, sleep quality, stress, and cognitive function relate to reproductive outcomes.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Voluntary written informed consent of the participant has been obtained prior to any screening procedures
* Age 18-43
* Planning to undergo MAR (eg, IUI, IVF, ICSI) - Physically able to cycle for cardiopulmonary exercise testing (CPET)
Exclusion Criteria:
* Any reduction in …
Inclusion Criteria:
* Voluntary written informed consent of the participant has been obtained prior to any screening procedures
* Age 18-43
* Planning to undergo MAR (eg, IUI, IVF, ICSI) - Physically able to cycle for cardiopulmonary exercise testing (CPET)
Exclusion Criteria:
* Any reduction in general state of health preventing from performing hormonal stimulation for MAR
* Absolute and relative contraindications for cardiopulmonary exercise testing (CPET) - No pregnancy at initial screening - Current illicit drug abuse including daily marijuana and CBD consumption (alcohol ≤2 drinks per day allowed)
* Any kind of severe chronic disease (e.g. severe heart failure, active cancer disease)
* Severe renal impairment (e.g. estimated glomerular filtration rate \<30 ml/min/m2)
* Known liver cirrhosis or other severe liver impairment
* Uncontrolled dysthyroidism
* Uncontrolled hypertension
* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, etc.
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