Kaempferol Absorption and Pharmacokinetics Evaluation
Recruiting
N/AInterventional Study
No DiseaseMitochondria HealthLongevityPharmacokinetics and Biological Absorption of Kaempferol in Healthy AdultHealthy Volunteers
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 70
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
120 (estimated)
Sponsor
University of Pittsburgh · Other
Who this trial is looking for
This trial is looking for healthy adults aged 18 to 70. Participants will take Kaempferol and provide blood and urine samples to help researchers understand how the body absorbs this compound.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 70 years old.
I am a healthy volunteer based on medical history.
I can understand the study procedures and give consent.
I am willing to follow all study procedures, including dietary restrictions.
I will not eat or drink restricted items during the study.
You may not be able to join if
I am allergic to Kaempferol or related compounds.
I am pregnant or breastfeeding.
I have significant acute or chronic medical conditions.
I have had an active or chronic infection.
I have cancer.
I have cardiovascular disease.
I have neurological disorders.
I donated blood within the last 8 weeks.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This study is a multi-site clinical trial designed to evaluate how the body absorbs and processes Kaempferol, a naturally occurring compound found in many plant-based foods. The primary purpose of the study is to measure the pharmacokinetics and biological absorption of Kaempferol in healthy adults.
Participants will receive Kaempferol and undergo scheduled blood and urine collections over a shor…
This study is a multi-site clinical trial designed to evaluate how the body absorbs and processes Kaempferol, a naturally occurring compound found in many plant-based foods. The primary purpose of the study is to measure the pharmacokinetics and biological absorption of Kaempferol in healthy adults.
Participants will receive Kaempferol and undergo scheduled blood and urine collections over a short study period. These samples will be used to measure Kaempferol levels in the body and to assess safety and tolerability. In addition, selected biological samples will be analyzed to explore molecular changes associated with Kaempferol exposure using advanced laboratory methods.
The study will be conducted at multiple research centers in the United States using a standardized protocol to ensure consistency across sites. The information collected will help improve understanding of how Kaempferol is absorbed and metabolized in humans and will support future research and regulatory evaluation.
Trial Locations
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Facility
City
State
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Status
Eligibility Criteria
Inclusion Criteria:
Adults aged 18 to 70 years
* Healthy volunteers as determined by medical history and screening assessment
* Ability to understand the study procedures and provide informed consent
* Willingness and ability to comply with all study procedures, including dietary restrictions, cli…
Inclusion Criteria:
Adults aged 18 to 70 years
* Healthy volunteers as determined by medical history and screening assessment
* Ability to understand the study procedures and provide informed consent
* Willingness and ability to comply with all study procedures, including dietary restrictions, clinic visits, blood draws, urine collection, and follow-up assessments
* Willingness to abstain from restricted foods, beverages, and supplements as specified in the study protocol during the study period
Exclusion Criteria:
* Known allergy or hypersensitivity to Kaempferol or related flavonoids
* Pregnancy or breastfeeding
* Presence of significant acute or chronic medical conditions that could increase risk or interfere with study outcomes, including but not limited to:
* Active or chronic infections
* Cancer
* Cardiovascular disease
* Neurological or neurodegenerative disorders
* Metabolic or systemic inflammatory conditions
* Use of prescription medications or supplements known to interfere with Kaempferol metabolism or pharmacokinetic assessment
* Blood donation within 8 weeks prior to study enrollment
* Participation in another interventional clinical study within a timeframe that could interfere with study results or participant safety
* Any condition or circumstance that, in the judgment of the study investigator, would make participation unsafe or compromise data integrity
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