Effect of Tegileridine Versus Sufentanil as Analgesic Components on Opioid-Induced Cough During Anesthesia Induction
Recruiting
N/A
Interventional Study
General Anesthetic Drug Adverse Reaction
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 190 (estimated)
- Sponsor
- The First People's Hospital of Lianyungang · Other
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About This Trial
In patients undergoing general anesthesia with planned tracheal intubation , a prospective, randomized, controlled study was conducted to record the occurrence of cough 2 minutes after injection of Sufentanil or Tegilerdine. The cough was graded based on the frequency and duration: Grade I, no cough; Grade II, a single mild cough; Grade III, multiple coughs with duration \<1 second; Grade IV, cont…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age between 18 and 65 years, 18 ≤ BMI (kg/m²) ≤ 30;
2. ASA grade I \~ III;
3. Scheduled elective surgery under general anesthesia with tracheal intubation.
Exclusion Criteria:
1. Patients with chronic cough (cough lasting \>8 weeks) or asthma;
2. Patients with a history of …
Contacts