Efficacy and Safety of Transcranial Magnetic Stimulation in Treatment of Alzheimer's Disease

Recruiting N/A Interventional Study
Alzheimer s Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
50 – 90
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
66 (estimated)
Sponsor
Fujian Medical University Union Hospital · Other
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About This Trial
This study is grounded in the regulatory mechanisms of the glymphatic system and applies repetitive transcranial magnetic stimulation (rTMS) to the treatment of Alzheimer's disease (AD). The clinical efficacy and safety of rTMS will be systematically evaluated. Furthermore, transcranial magnetic stimulation-evoked potentials (TMS-EEG) and functional near-infrared spectroscopy (fNIRS) will be emplo…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Meets the 2018 NIA-AA diagnostic criteria for Alzheimer's disease (AD) * Meets DSM-5 diagnostic criteria * Mild to moderate disease severity (CDR Global Score 1 to 2) * Evidence of AD pathology: positive amyloid PET OR positive cerebrospinal fluid (CSF) AD biomarkers OR positi…
Contacts

Xiaodong Pan

13395080173

panxd@fjmu.edu.cn

CONTACT