This study aims to explore the effect of burst-taVNS (electric stimulation of the concha cymba) on tonic (capsaicin-induced skin pain) and acute (pressure pain sensitivity) experimental pain and cardioception. Primary outcomes include pain intensity. Secondary outcomes include sensory thresholds, resting heart rate (EKG), pupillary measurements and conditioned pain modulation.
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
* Healthy
* Speak and understand English
* 18-60 years old.
Exclusion Criteria:
* Pregnant and/or breastfeeding
* Regular use of cannabis, opioids or other drugs
* Current or previous neurologic, musculoskeletal, mental, or other illnesses (e.g., brain or spinal cord injuries,…
Inclusion Criteria:
* Healthy
* Speak and understand English
* 18-60 years old.
Exclusion Criteria:
* Pregnant and/or breastfeeding
* Regular use of cannabis, opioids or other drugs
* Current or previous neurologic, musculoskeletal, mental, or other illnesses (e.g., brain or spinal cord injuries, degenerative neurological disorders, major depression, cardiovascular disease, chronic lung disease, etc.)
* Current regular (once or more a week) use of analgesic medication or other medication which may affect the trial (including paracetamol and NSAIDs)
* Recent history of acute pain particularly in the lower limbs
* Abnormally disrupted sleep in 24 hours preceding experiment
* Contraindications to electric stimulation application (history of epilepsy, metal implants in head or jaw, etc.)
* Lack of ability to cooperate
* Contraindications for capsaicin including an intolerance chili consumption and burns or wounds to the application site.
Contacts
No contact information available.
What are you hoping to find?
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.