Analysis of the Role of IgE Proteoforms in Health and Disease

Recruiting Observational Study
Anaphylaxis Mastocytosis X-linked Agammaglobulinaemia Venom Allergy Chronic Spontaneous Urticaria (CSU) Type I Allergy Medication Allergy Healthy Control Hereditary Alpha-Tryptasemia
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
200 (estimated)
Sponsor
KU Leuven · Other
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About This Trial
The goal of this observational study is to evaluate the role of IgE proteoforms in healthy volunteers and in patients with type I allergy, patients with chronic spontaneous urticaria, patients with a recent history of anaphylaxis, patients with mastocytosis, patients with hereditary alpha tryptasemia, patients with X-linked agammaglobulinemia (XLA), and patients undergoing desensitization for veno…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * CSU and type I allergic diseases (including anaphylaxis and desensitization), atopic dermatitis, mastocytosis, XLA and HaT (informed consent, age: any available adult subject, gender: any available subject, clinical phenotype and specific information about the allergy (e.g. se…
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