ALSS - DPMAS and Therapeutic Plasma Exchange (TPE), Its Effect on Primary Coagulation, Inflammation and the Function of Vital Organs in ALF or ACLF

Recruiting N/A Interventional Study
Acute Liver Failure
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 75
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
25 (estimated)
Sponsor
Institute for Clinical and Experimental Medicine · Government
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About This Trial

The artificial liver support system (ALSS) in patients with acute on chronic liver failure - the use of combined molecular adsorption system with double plasma (DPMAS) and therapeutic plasma exchange (TPE), its effect on primary coagulation, inflammation and the function of vital organs.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Adult patient, age ≥18 years * Expressed consent to the inclusion * Patient hospitalized on ICU with ALF or ACLF diagnosis * Recently meeting the inclusion to liver transplantation * Present on a waiting list to liver transplant * Unsuitable for inclusion to liver transplantat…
Contacts

Petr Piza, MD, MHA

+420 602 225 077

petr.piza@ikem.cz

CONTACT

Eva Kieslichova, ass. prof., MD, PhD

+420 261 363 350

evki@ikem.cz

CONTACT