Clinical Study of Intrastromal Anti-VEGF Injection for Corneal Neovascularization.

Recruiting Phase 1 Phase 2 Interventional Study
Herpes Simplex Keratitis Corneal Neovascularization
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1/2
Study type
Interventional
Purpose
Treatment
Participants needed
100 (estimated)
Sponsor
Second Affiliated Hospital, Zhejiang University, School of Medicine · Other
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About This Trial
Corneal stromal injection is an emerging local drug delivery method, characterized by strong targeting, high drug concentration, and prolonged duration of action. It has been preliminarily applied in the treatment of fungal keratitis and neurotrophic corneal diseases. This study aims to investigate the safety and efficacy of anti-VEGF drugs delivered via corneal stromal injection in neovasculariza…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Diagnosis: Patients who meet the diagnostic criteria for Herpes Simplex Virus (HSV) keratitis with neovascularization. * Age: Adults aged 18 years or older. * Previous Treatment: Patients who have not undergone other anti-VEGF treatments or corneal surgeries. * Informed Consen…
Contacts

Xiuming Jin

8613989455778

lzyjxm@zju.edu.cn

CONTACT