Efficacy of Topical Coenzyme Q10 and Curcumin for Oral Leukoplakia Treatment
Recruiting
N/A
Interventional Study
Oral Leukoplakia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 40 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 34 (estimated)
- Sponsor
- Alexandria University · Other
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About This Trial
Oral leukoplakia (OL) is recognized as the most common potentially malignant disorder of the oral mucosa. The pathogenesis of OL is complex and multifactorial, with oxidative stress playing a central role. Topical antioxidants have gained attention as therapeutic options to help stabilize lesions and potentially prevent malignant transformation. Both CoQ10 and curcumin have demonstrated a clinical…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Clinically and histologically diagnosed with homogeneous oral leukoplakia not indicated for surgical excision .
* Lesions accessible for topical application.
* Willing to sign informed consent and comply with study instructions and return to follow up
Exclusion Criteria:
* M…
Contacts