Urinary Titin Biomarker in DMD

Recruiting N/A Interventional Study
Duchenne Muscular Dystrophy (DMD) Becker's Muscular Dystrophy (BMD)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
2 – 10
Sex
Male
Study type
Interventional
Purpose
Basic Science
Participants needed
50 (estimated)
Sponsor
Children's Hospital of Philadelphia · Other
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About This Trial
A universal challenge in clinical investigation of novel therapeutics is the need for quantitative, objective biomarkers that directly address the mechanisms of disease and provide information relevant to clinically meaningful functional improvement. This has been a particular challenge in rare and slowly progressive diseases such as Duchenne Muscular Dystrophy (DMD). The investigators hypothesiz…
Trial Locations
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Eligibility Criteria
DMD/BMD Subject Inclusion/Exclusion Criteria Inclusion Criteria: 1. Ambulatory at screening 2. Genetically confirmed diagnosis of DMD/BMD 3. Parental/guardian permission (informed consent) for children. Child assent will also be obtained from patients ages 7 years old and older and deemed by the i…
Contacts

Calliope O'Donnell, MS

267-426-7786

odonnellcs@chop.edu

CONTACT

Julianne Larosa, MPH

267-426-7875

Larosaj1@chop.edu

CONTACT