Transcranial Magnetic Stimulation for PTSD

Transcranial Magnetic Stimulation in Veterans With PTSD

Recruiting N/A Interventional Study
PTSD - Post Traumatic Stress Disorder
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
19 – 70
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
20 (estimated)
Sponsor
White River Junction Veterans Affairs Medical Center · Federal
Who this trial is looking for

This trial is looking for veterans with moderate to severe PTSD. Participants will receive ten treatment sessions and undergo brain scans and some health tests.

Are You a Good Fit for This Trial?
Must not be taking ClozapineBupropion
Rules you out PsychosisManiaSeizuresCentral nervous system disorder

You may be able to join if

  • I am between 19 and 70 years old.
  • I can get VA healthcare.
  • I have been diagnosed with moderate to severe PTSD.
  • I agree to have my PTSD assessment recorded.
  • I can have my Motor Threshold tested.
  • If I am a woman, I use birth control.
  • I can read and sign the consent form.

You may not be able to join if

  • I am pregnant or breastfeeding.
  • I cannot have an MRI scan.
  • I use clozapine or bupropion above 300mg.
  • I have a pacemaker or defibrillator.
  • I have metal in my head besides dental work.
  • I have had a significant brain disorder.
  • I have had a seizure in the last year.
  • I have current psychosis or mania.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial
With this research investigators hope to begin to understand how rTMS can improve posttraumatic stress disorder (PTSD) symptoms. TMS improves PTSD through two interrelated mechanisms: change in brain limbic system function and change in systemic inflammatory activation. Participants who decide to join this study, will receive ten rTMS treatments. All participants will undergo a 40-minute rTMS proc…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age between 19 and 70 * Eligible for VA healthcare * Moderate to severe PTSD as determined by a total score of at least 25 on the CAPS within 7 days of randomization. * Agree to have CAPS audio recorded. * Ability to obtain a Motor Threshold using the TMS device during screeni…
Contacts

Bradley V Watts, MD, MPH

802-295-9363

bradley.watts@va.gov

CONTACT

Julian Sewall

603-266-7140

julian.sewall@va.gov

CONTACT