MG2512 Injection for Advanced Solid Tumors

A Study of MG2512 Injection in Participants With Advanced Solid Tumors

Recruiting Phase 1 Interventional Study
Advanced Solid Tumor
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 75
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
116 (estimated)
Sponsor
Shanghai Mabgen Biopharmaceutical Technology Co., Ltd. · Industry
Who this trial is looking for

This trial is looking for adults with advanced solid tumors that can't be cured with standard treatments. Participants will receive MG2512 injection and help researchers understand its safety and effectiveness.

Are You a Good Fit for This Trial?
Rules you out Active hepatitis BHIV positiveActive pulmonary tuberculosis

You may be able to join if

  • I am between 18 and 75 years old.
  • I can provide written consent to participate.
  • I have advanced solid tumors that have progressed after standard treatment.
  • I have at least one measurable tumor.
  • I expect to live for at least 3 months.
  • I have a good performance status and can take part in the trial.
  • I can provide tumor tissue for testing.
  • I will use contraception during the trial.

You may not be able to join if

  • I have a history of brain metastasis or related symptoms.
  • I have had another cancer in the last 5 years.
  • I have severe heart or blood vessel diseases.
  • I have uncontrolled pain or symptoms from my tumor.
  • I have had severe infections in the past month.
  • I have a serious lung disease that affects my breathing.
  • I had any major bleeding in the last 3 months.
  • I cannot wait 4 weeks after my last cancer treatment before starting this trial.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

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About This Trial

This is an open-label, multi-center, multiple dose Phase 1 study to evaluate the safety, tolerability, pharmacokinetics and efficacy of MG2512 injection in participants with advanced solid tumors.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Voluntary participation and written informed consent. 2. 18-75 years old, no gender limitation. 3. Eastern Cooperative Oncology Group (ECOG) score: 0-1. 4. With a life expectancy ≥ 3 months. 5. Patients with recurrent or metastatic solid tumors that have been histologically o…
Contacts

Rongfu Mao

+86-021-61053363

rongfu.mao@hengrui.com

CONTACT

Hao Shen

+86-021-61053363

hao.shen@hengrui.com

CONTACT