The Effect of Blood Carboxyhemoglobin Levels on NF-kB, NRF2 and PGC-1α During Low-flow and Normal-flow Anesthesia
Recruiting
N/A
Interventional Study
Anesthesia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 70
- Sex
- Any
- Study type
- Interventional
- Purpose
- Health Services Research
- Participants needed
- 120 (estimated)
- Sponsor
- Ataturk Training and Research Hospital · Other
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Carbon monoxide (CO) is a colorless, odorless, and tasteless gas that exerts diverse biological effects across tissues and organs. At high concentrations, it is recognized as toxic because of harmful effects such as tissue hypoxia, oxidative stress, peroxynitrite formation, inflammation, apoptosis, and immune damage. However, the endogenous production of CO suggests that it may confer protective m…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
aged 18-70 years
classified as ASA I
scheduled for inhalational anesthesia lasting ≥2 hours
Exclusion Criteria:
Patients with cardiovascular disease, respiratory system disease, hepatic or renal disease
pregnant or breastfeeding women
trauma patients
those undergoing emer…
Contacts
No contact information available.