The Relationship Between Serum S100B and Brain-Derived Neurotrophic Factor
Recruiting
Observational Study
Fibromyalgia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 50
- Sex
- Female
- Study type
- Observational
- Participants needed
- 60 (estimated)
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital · Other
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About This Trial
Fibromyalgia is a chronic pain syndrome characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and cognitive symptoms. Central sensitization is considered a key mechanism in the pathophysiology of fibromyalgia; however, the underlying biological markers have not been fully clarified.
Brain-derived neurotrophic factor (BDNF) and S100B protein have been suggested to play rol…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Female participants aged between 18 and 50 years
Diagnosis of fibromyalgia according to 2016 American College of Rheumatology (ACR) criteria
Symptoms present for at least 3 months
Ability to understand and complete study questionnaires
Provision of written informed consent…
Contacts