Non-Invasive Preimplantation Genetic Screening for Aneuploidies and Clinical Outcomes in Egg Donation Patients
Recruiting
Observational Study
IVF
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 50
- Sex
- Female
- Study type
- Observational
- Participants needed
- 164 (estimated)
- Sponsor
- Instituto Bernabeu · Other
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About This Trial
Preimplantation genetic testing for aneuploidies (PGT-A) is commonly used in IVF but requires embryo biopsy and shows limited benefit in egg donation cycles. Non-invasive PGT-A (niPGTA), based on the analysis of cell-free embryonic DNA in spent culture media, offers a promising biopsy-free alternative. This prospective, blinded study in egg donation cycles will evaluate whether niPGTA-detected ane…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Women between 18 and 50 years old who are oocyte recipients.
* Signed consent form
* Transfer of a single blastocyst-stage embryo
* Male with normal sperm FISH
Exclusion Criteria:
* Uterine malformations
* Abnormal karyotypes in either partner
* Failure to sign informed cons…
Contacts
No contact information available.