Exploratory Study of EBV-TCR-T Cell Injection for EBV DNAemia After Allogeneic Hematopoietic Stem Cell Transplantation

Recruiting Phase 1 Phase 2 Interventional Study
Epstein-Barr Virus Infection Post-Transplant Lymphoproliferative Disorder
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 70
Sex
Any
Trial phase
Phase 1/2
Study type
Interventional
Purpose
Treatment
Participants needed
18 (estimated)
Sponsor
Daihong Liu · Other
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About This Trial
Epstein-Barr virus (EBV) DNAemia is a common and potentially serious complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT) and may progress to EBV-associated lymphoproliferative disorders. Current treatment options are limited, and effective immune-based therapies are still needed. This is an investigator-initiated, exploratory, open-label, single-arm clinical study de…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years at the time of enrollment. * History of allogeneic hematopoietic stem cell transplantation. * Presence of Epstein-Barr virus (EBV) DNAemia confirmed by quantitative polymerase chain reaction (qPCR) in peripheral blood. * EBV DNAemia persisting or increasing desp…
Contacts

Daihong Liu

+8613681171597

daihongrm@163.com

CONTACT

Liping Dou

+8613681207138

lipingruirui@163.com

CONTACT