Impact of Vitamin D Therapy on Thyroid Function and Antibody Levels in Pediatric Graves' Disease
Recruiting
Phase 2
Interventional Study
Graves Disease
Graves' Disease
Hyperthyroidism
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 9 – 17
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 30 (estimated)
- Sponsor
- Northwell Health · Other
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About This Trial
The goal of this randomized pilot feasibility clinical trial is to determine the feasibility of implementing a protocol for a larger trial to assess the effects of high-dose vitamin D supplementation in pediatric patients (9-17 years old) newly diagnosed with Graves' disease. The main questions it aims to answer are:
What are the recruitment and adherence rates for a larger trial using this proto…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* All new pediatric participants aged 9-17 years with a new diagnosis of GD who will be started on methimazole, will be offered to participate at the time of diagnosis.
* Biochemical features include:
* Suppressed TSH \<0.1.
* Elevated T3
* Elevated Free T4
* Elevated T4
* Posit…
Contacts