HOXB7 and Linked Tissue and Blood Biomarkers in the Lungs of Patients With Pulmonary Fibrosis
Recruiting
Observational Study
Fibrosis, Pulmonary
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Study type
- Observational
- Participants needed
- 80 (estimated)
- Sponsor
- University of Modena and Reggio Emilia · Other
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About This Trial
This pilot, multicenter, interventional study investigates the expression of HOXB7 and its associated molecular pathway in lung tissue and blood-derived exosomes from patients with pulmonary fibrosis (PF), including idiopathic pulmonary fibrosis (IPF). Using RNA sequencing (RNA-Seq) and proteomic analysis via mass spectrometry (MS), the study aims to identify tissue and circulating biomarkers asso…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adults aged 18 to 80 with clinical suspicion of pulmonary fibrosis
* Availability of fresh lung tissue from biopsy or lung explant
* Signed informed consent for research use of biological material and data
Exclusion Criteria:
\- Refusal to sign informed consent
Contacts