Emergency Department Implementation of the i-STAT Alinity Traumatic Brain Injury Whole Blood Test

Recruiting Observational Study
TBI (Traumatic Brain Injury) Implementation Research
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
340 (estimated)
Sponsor
Shawn Eagle · Other
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About This Trial
The objective of this study is to identify determinants for implementing the i-STAT Alinity whole blood traumatic brain injury (TBI) test for its Food and Drug Administration (FDA)-indicated use and to evaluate other potential outcomes with clinical implications. The main questions it aims to answer are: 1. Determine the number of patients with non-elevated (i.e., below clinical cutoff) whole blo…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Aged 18 or older 2. Presenting to an enrolling ED with ED Arrival GCS of 13-15 following reported head blunt impact within 24 hours of injury 3. Meets Department of Defense (DoD) definition of mTBI: A traumatically induced physiological disruption of brain function as a resu…
Contacts

Shawn Eagle, PhD

412-624-2041

eaglesr2@upmc.edu

CONTACT

Kathryn Edelman, MS

412-624-1077

dunfeekl@upmc.edu

CONTACT