Dexamethasone for Quality of Life After Hip Surgery
The Effect of Corticosteroids on Quality of Life Following Total Hip Arthroplasty: HIPSTER Study
Recruiting
Phase 4
Interventional Study
Postoperative Quality of Recovery
Health-Related Quality-of-Life
Quality of Life
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 60 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 224 (estimated)
- Sponsor
- Ziekenhuis Oost-Limburg · Other
Who this trial is looking for
This trial is looking for older adults who are having total hip replacement surgery. Participants will receive a single dose of either 5 mg or 25 mg of dexamethasone during the surgery to see how it affects their recovery and quality of life up to three months later.
Are You a Good Fit for This Trial?
You may be able to join if
- I am 60 years old or older.
- I am scheduled for elective total hip arthroplasty.
- I will have the procedure under spinal anaesthesia.
You may not be able to join if
- I am having hip revision surgery.
- I am having both hips replaced at the same time.
- I am allergic to dexamethasone or other corticosteroids.
- I have been taking corticosteroids every day for more than 4 weeks in the last 3 months.
- I have active gastric or intestinal ulcers.
- I cannot give informed consent.
- I need urgent, non-elective surgery.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
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Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Total hip arthroplasty (THA) is a highly effective and commonly performed procedure for end-stage osteoarthritis. Perioperative inflammation contributes to postoperative pain, fatigue, and delayed recovery. Dexamethasone, a potent glucocorticoid with strong anti-inflammatory properties, is widely used in orthopedic surgery and incorporated into Enhanced Recovery After Surgery (ERAS) protocols for …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* aged 60 years or older;
* scheduled for elective total hip arthroplasty;
* procedure under spinal anaesthesia.
Exclusion Criteria:
* hip revision surgery (reoperation);
* bilateral total hip arthroplasty during the same procedure;
* known hypersensitivity to dexamethasone or…
Contacts