Decoupling Immunotherapy Toxicity and Cancer Response

Recruiting Observational Study
Tumor Cardiovascular
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
1,200 (estimated)
Sponsor
M.D. Anderson Cancer Center · Other
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About This Trial

This study is a novel evaluation of cardiotoxicity after ICI therapy based on traditional CV risk factors with the addition of metabolomic profiles, epigenetic aging, and CHIP. It is not an extension of previous work in ICI therapy.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Age ≥ 18 years 2. Plan to start immune checkpoint inhibitor for cancer therapy Exclusion Criteria: 1. No baseline blood collection prior to initiation 2. At time of evaluation not determined to be a good candidate for evaluation of outcome events by the principal investigat…
Contacts

Nicolas Palaskas, MD

832-750-1109

nlpalaskas@mdanderson.org

CONTACT