No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
21 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
6 (estimated)
Sponsor
Cairo University · Other
Who this trial is looking for
This trial is looking for adults who need a special healing collar after dental surgery. Participants will receive oxygen therapy to see if it helps the healing process around dental implants.
Are You a Good Fit for This Trial?
You may be able to join if
I am 21 years old or older.
I need a customized healing collar after my dental surgery.
I am generally healthy.
I can provide written informed consent.
I will attend follow-up visits.
You may not be able to join if
I am under 21 years old.
I have a systemic disease that affects healing.
I smoke or use tobacco.
I am pregnant or breastfeeding.
I take medications that affect soft tissue healing.
I am currently receiving chemotherapy or radiotherapy.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The preservation and enhancement of peri-implant soft tissues are essential for the long-term success and esthetic integration of dental implants. Customized healing abutments have been introduced to support individualized soft tissue shaping; however, optimizing soft tissue healing around implants remains a clinical challenge. Oxygen plays a critical role in wound healing by promoting angiogenesi…
The preservation and enhancement of peri-implant soft tissues are essential for the long-term success and esthetic integration of dental implants. Customized healing abutments have been introduced to support individualized soft tissue shaping; however, optimizing soft tissue healing around implants remains a clinical challenge. Oxygen plays a critical role in wound healing by promoting angiogenesis, fibroblast proliferation, and collagen synthesis. Topical oxygen therapy has shown promise in accelerating tissue regeneration, yet its application in oral implantology, particularly in conjunction with customized healing abutments, has not been adequately studied. This study aims to provide clinical evidence regarding the effectiveness of topical oxygen therapy in improving linear and volumetric soft tissue changes around dental implants. The findings may guide clinicians in refining soft tissue management protocols and contribute to establishing evidence-based practices in implant dentistry.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Adults aged 21 years and above.
* Indicated for customized healing collar placement after second-stage surgery.
* Good general health.
* Able and willing to provide written informed consent.
* Committed to follow-up visits.
Exclusion Criteria:
* Individuals below 21…
Inclusion Criteria:
* Adults aged 21 years and above.
* Indicated for customized healing collar placement after second-stage surgery.
* Good general health.
* Able and willing to provide written informed consent.
* Committed to follow-up visits.
Exclusion Criteria:
* Individuals below 21 years old.
* Systemic diseases affecting healing.
* Smokers/tobacco users.
* Pregnant/lactating women.
* Medications affecting soft tissue healing.
* Chemotherapy/radiotherapy patients.
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