Speech-based Assessment of Relapse Risk in People With Psychosis

Healthy participants Inclusion Criteria: * Between 18 and 65 years old. * Subjects must be able to provide informed consent (IC). * Participants must have provided signed informed consent prior to enrollment. * Participants should not take prescription drugs regularly. * Native or equivalent fluency in speaking and understanding one of the following languages: English, German, Dutch, French, Czech or Turkish. * Ability to have access to a smartphone and be capable of using a mobile app for speech-based data collection. * Must be able to comply with the study schedule and procedures. Healthy participants Exclusion Criteria: * Any history of major diseases (e.g., cardiovascular, neurological, metabolic, renal, hepatic, respiratory or speech disorders). * Recreational drug use or psychiatric disorders due to use of alcohol. * Depression, anxiety, or other psychiatric disorders. * Family history of depression, anxiety, or other psychiatric disorders. * Individuals who are not able or willing to understand the purpose and details of the study. Individuals with psychosis Inclusion Criteria: * Between 18 and 65 years old. * Diagnoses include psychotic disorders (schizophrenia, schizoaffective disorder, schizophreniform disorder, acute psychosis, bipolar disorder with psychotic symptoms, psychosis not otherwise specified). * First visit must be during remission phase (baseline measurement). * Current positive symptoms rated 3 (mild) or lower on all of these Brief Psychiatric Symptom Scale (BPRS) items: hallucinatory behavior, unusual thought content, conceptual disorganization. * Must be able to comply with the study schedule and procedures. * Subjects must be able to provide IC. * Participants must have provided signed informed consent prior to enrollment. * Native or equivalent fluency in speaking and understanding one of the following languages: English, German, Dutch, French, Czech or Turkish. * Ability to have access to a smartphone and be capable of using a mobile app for speech-based data collection. Individuals with psychosis Exclusion Criteria: * Severe comorbid speech disorders (aphasia or severe stuttering) that prevent adequate speech recording. * Individuals who are not able or willing to understand the purpose and details of the investigation. Citizens with psychiatric or somatic comorbidity, drug- or alcohol abuse will be allowed to participate, so that the sample will reflect the general population of citizens with psychosis and the study's endpoints will be generalizable.