Clinical Outcome Assessment for AT & BCI

Enrollment will involve three different cohorts, namely a cohort of healthy participant, a cohort of ALS/SCI participant who underwent the implant of an invasive BCI device, and a cohort of ALS/SCI participants without any implanted BCI device. Below are listed the inclusion and exclusion criteria for each diagnostic group. Spinal Cord Injury (SCI): Inclusion Criteria: * Age at or above 18 years old; * Diagnosis of spinal cord injury, at the level of T1 or above levels (between C1 and T1); * Ability to communicate independently or with a support device, or with a legal representative; * Ability to participate in a study session for about 3 hours (e.g., endurance, fatigue), which may include breaks as needed. Exclusion Criteria: * Participation in another trial that would conflict with the current study or clinical endpoint interference may occur. Amyotrophic Lateral Sclerosis (ALS): Inclusion criteria: * Age at or above 18 years old; * Diagnosis of amyotrophic lateral sclerosis; * Ability to communicate independently, with a support device, or with a legal representative; * Ability to participate in a study session for about 3 hours (e.g., endurance, fatigue), which may include breaks as needed. Exclusion criteria: ● Participation in another trial that would conflict with the current study or clinical endpoint interference may occur. Healthy Controls: Inclusion criteria: * Age at or above 18 years old; * No history of neurological or psychiatric disorders; * Ability to provide written informed consent; * Ability to participate in a study session for about 3 hours (e.g., endurance, fatigue), which may include breaks as needed. Exclusion criteria: * Participation in another trial that would conflict with the current study or clinical endpoint interference may occur; * Cognitive, visual, or auditory deficits that would interfere with study participation; * Current or prior diagnosis or condition that could confound study assessments.