Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With "Classic" Polycystic Ovary Syndrome (PCOS)
Recruiting
N/A
Interventional Study
Polycystic Ovary Syndrome
Familial Partial Lipodystrophy
LMNA (LaMin Nuclear A) Related Disorders
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 45
- Sex
- Female
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 81 (estimated)
- Sponsor
- Assistance Publique - Hôpitaux de Paris · Other
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About This Trial
Diagnostic case-control study (1 case for 2 controls). Inclusion of patients with severe insulin resistance syndrome of genetic origin, then inclusion of controls: patients examined for PCOS in day hospital with matching age (+/- 5 years) and Body mass index (+/- 5kg/m2).
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Women aged ≥ 18 years and \< 45 years ;
* Discontinuation of estrogen-progestin therapyfor at least 3 months ;
* Signed informed consent ;
* Social security affiliation.
Case (n=25):
\- Patient with a lipodystrophic syndrome due to a known pathogenic variant of the LMNA gene…
Contacts