Germline Genetic Testing of the TP53 Gene
Recruiting
Observational Study
TP53 Gene Mutation
Multi-Gene Transcriptional Profiling
TP53 Gene Germline Mutation Carrier
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 90
- Sex
- Any
- Study type
- Observational
- Participants needed
- 1,940 (estimated)
- Sponsor
- European Institute of Oncology · Other
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About This Trial
This is a retrospective, observational, single-center study designed as a cohort analysis. The study population will include consecutive patients referred for genetic counseling and TP53 germline genetic testing between 2004 and 2025 at the Division of Cancer Prevention and Genetics of the IEO. The primary endpoint is to determine the overall detection rate of Pathological Variants (PVs) in the TP…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Have undergone at least one genetic counseling session at the Division of Cancer Prevention and Genetics of the IEO;
* Have undergone germline TP53 genetic testing, regardless of the referral criteria for counseling and/or testing or the approach used;
* Have provided written …
Contacts