Perioperative Outcomes After Neoadjuvant Therapy in Colorectal Cancer
Recruiting
Observational Study
Colorectal Carcinoma (CRC)
Complications
Neoadjuvant Therapy
Endothelial Dysfunction
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 68 (estimated)
- Sponsor
- Osijek University Hospital · Other
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About This Trial
This prospective study investigates the effects of neoadjuvant therapy on endothelial function, microvascular tissue density, and tissue fibrosis in patients with colorectal cancer and their association with perioperative complications. The primary objective is to assess differences in microvascular tissue density between patients who received neoadjuvant therapy and those who did not, biomarkers,…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adults aged ≥18 years with histologically confirmed colorectal cancer
* Planned surgical treatment for colorectal cancer (either laparoscopic LPSC or open laparotomy)
* Ability to understand the study protocol and provide written informed consent.
* Both sexes
* ASA classifica…
Contacts