Vagus Nerve Stimulation for Cognitive Improvement

Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations

Recruiting N/A Interventional Study
Mild Cognitive Impairment (MCI) Parkinsons Disease (PD) Healthy Adult
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 65
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
80 (estimated)
Sponsor
University of Colorado, Denver · Other
Who this trial is looking for

This trial is looking for healthy adults and people with Parkinson's disease aged 18-65 to understand how stimulating the vagus nerve can help with thinking abilities. Participants will receive gentle electrical stimulation applied to the ear during the study.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am aged 18-65.
  • I can sign informed consent.
  • I can follow instructions.
  • I have been diagnosed with Parkinson's disease without severe impairments.

You may not be able to join if

  • I have a current significant medical condition.
  • I have abnormal ear anatomy or an active ear infection.
  • I have electronic medical implants like pacemakers or neuro-stimulators.
  • I have uncorrected visual impairments that would affect my performance.
  • I have other significant diseases or disorders that might impair my participation.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

This study plans to learn more about how stimulating the vagus nerve through gentle electrical stimulation applied to the ear can affect decision-making, problem-solving, and other thinking abilities. This process, called transcutaneous auricular vagus nerve stimulation (taVNS), could help improve brain function in both healthy individuals and people with Parkinson's disease (PD).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Individuals aged 18-65. 2. Ability to sign informed consent. 3. Ability to follow written and verbal instructions. 4. For the PD group, a clinical diagnosis of Parkinson's disease without severe motor or cognitive impairments. Exclusion Criteria: 1. Current uncontrolled and…
Contacts

Elise R Carter

3094335932

elise.carter@cuanschutz.edu

CONTACT