No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 65
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
80 (estimated)
Sponsor
University of Colorado, Denver · Other
Who this trial is looking for
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Answer a few quick questions to see if you may meet the eligibility requirements.
This study plans to learn more about how stimulating the vagus nerve through gentle electrical stimulation applied to the ear can affect decision-making, problem-solving, and other thinking abilities. This process, called transcutaneous auricular vagus nerve stimulation (taVNS), could help improve brain function in both healthy individuals and people with Parkinson's disease (PD).
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Individuals aged 18-65.
2. Ability to sign informed consent.
3. Ability to follow written and verbal instructions.
4. For the PD group, a clinical diagnosis of Parkinson's disease without severe motor or cognitive impairments.
Exclusion Criteria:
1. Current uncontrolled and…
Inclusion Criteria:
1. Individuals aged 18-65.
2. Ability to sign informed consent.
3. Ability to follow written and verbal instructions.
4. For the PD group, a clinical diagnosis of Parkinson's disease without severe motor or cognitive impairments.
Exclusion Criteria:
1. Current uncontrolled and/or clinically significant medical condition.
2. Abnormal ear anatomy or active ear infection.
3. Electronic medical implants, such as pacemakers, cochlear prosthesis, neuro-stimulators.
4. Uncorrected visual impairments that would interfere with task performance.
(6) Other significant diseases or disorders that might impair study participation.
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