HELIOS Advanced: Human Oocyte Illumination to Enhance Development

Recruiting N/A Interventional Study
IVF Outcomes
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 48
Sex
Female
Study type
Interventional
Purpose
Treatment
Participants needed
270 (estimated)
Sponsor
Columbia University · Other
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About This Trial
Oocytes need a lot of energy to complete meiosis and fertilize successfully. As women get older, the "power plants" of the cells (called mitochondria) don't work as well. This makes it harder for eggs and embryos to develop normally. One possible way to help is with a gentle light treatment called photobiomodulation (PBM). This uses a special type of red light that boosts energy production in cell…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Female age between 18-48 years at the time of the IVF/ICSI cycle * Undergoing blastocyst culture * Using own oocytes * Has at least two oocytes available for randomization * Consenting to oocyte level randomization * Plan to transfer euploid embryo within 6 months Exclusion C…
Contacts

Samuel Zev Williams, MD, PhD

646-756-8282

zw2421@cumc.columbia.edu

CONTACT

Laura C Gemmell, MD, MSc

646-756-8282

lg3094@cumc.columbia.edu

CONTACT